The structure of (S)-5-(3-acetyl-5-chloro-2-ethoxy-6-fluorophenyl)-2-oxazolidinone, C(13)H(13)ClFNO(4), at 100â K has monoclinic (P2(1)) symmetry. The compound has a polymeric structure propagated by a screw axis parallel to the b axis with N-Hâ¯O hydrogen bonding. It is of inter-est with respect to efforts in the synthesis of a candidate anti-cancer drug, parsaclisib.
Crystal structure of (S)-5-(3-acetyl-5-chloro-2-ethoxy-6-fluorophenyl)-2-oxazolidinone.
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作者:Li Victor, Yap Glenn P A, Ni Chaoying
| 期刊: | Acta Crystallographica Section E: Crystallographic Communications | 影响因子: | 0.500 |
| 时间: | 2024 | 起止号: | 2024 Mar 19; 80(Pt 4):375-377 |
| doi: | 10.1107/S2056989024001920 | ||
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