Crystal structures of two new 3-(2-chloro-eth-yl)-r(2),c(6)-diarylpiperidin-4-ones.

The syntheses and crystal structures of 3-(2-chloro-eth-yl)-r-2,c-6-di-phenyl-piperidin-4-one, C(19)H(20)ClNO, (I), and 3-(2-chloro-eth-yl)-r-2,c-6-bis-(4-fluoro-phen-yl)piperidin-4-one, C(19)H(18)ClF(2)NO, (II), are described. The piperidone ring adopts a chair conformation in (I), whereas a slightly distorted chair conformation is formed in (II). The dihedral angle between the mean plane of the phenyl rings is 59.1†(1)° in (I) and 76.1†(1)° in (II). The crystal packing features weak inter-molecular N-H⋯O hydrogen bonds in each structure.