The title compound, C(23)H(18)FNO(4), crystallized as a racemate. It exhibits a cis conformation with respect to the F atom and the methine H atom. The piperidine ring has a screw-boat conformation. The meth-oxy-phenyl ring and the phenyl ring are inclined to the mean plane of the iso-quinoline ring system by 89.85â (4) and 46.62â (5)°, respectively, and by 78.15â (5)° to one another. In the crystal, mol-ecules are linked by an O-Hâ¯O hydrogen bond forming chains propagating along the a-axis direction. The chains are linked by C-Hâ¯F hydrogen bonds, forming layers lying parallel to the ab plane.
Crystal structure of (3S*,4R*)-4-fluoro-3-(4-meth-oxy-phen-yl)-1-oxo-2-phenyl-1,2,3,4-tetra-hydro-iso-quinoline-4-carb-oxy-lic acid.
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作者:Lehmann Anna, Lechner Lisa, Radacki Krzysztof, Braunschweig Holger, Holzgrabe Ulrike
| 期刊: | Acta Crystallographica Section E: Crystallographic Communications | 影响因子: | 0.500 |
| 时间: | 2017 | 起止号: | 2017 May 23; 73(Pt 6):867-870 |
| doi: | 10.1107/S2056989017007186 | ||
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