Nine polyketides, including two new benzophenone derivatives, peniphenone (1) and methyl peniphenone (2), along with seven known xanthones (3-9) were obtained from mangrove endophytic fungus Penicillium sp. ZJ-SYâ isolated from the leaves of Sonneratia apetala. Their structures were elucidated on the basis of MS, 1D, and 2D NMR data. Compounds 1, 3, 5, and 7 showed potent immunosuppressive activity with IC(50) values ranging from 5.9 to 9.3 μg/mL.
Polyketides with Immunosuppressive Activities from Mangrove Endophytic Fungus Penicillium sp. ZJ-SYâ.
阅读：3
作者：Liu Hongju, Chen Senhua, Liu Weiyang, Liu Yayue, Huang Xishan, She Zhigang
| 期刊： | Marine Drugs | 影响因子： | 5.400 |
| 时间： | 2016 | 起止号： | 2016 Nov 25; 14(12):217 |
| doi： | 10.3390/md14120217 | ||
特别声明
1、本文转载旨在传播信息，不代表本网站观点，亦不对其内容的真实性承担责任。
2、其他媒体、网站或个人若从本网站转载使用，必须保留本网站注明的“来源”，并自行承担包括版权在内的相关法律责任。
3、如作者不希望本文被转载，或需洽谈转载稿费等事宜，请及时与本网站联系。
4、此外，如需投稿，也可通过邮箱info@biocloudy.com与我们取得联系。