Non-Enzymatic Glucose Biosensor Based on Highly Pure TiO(2) Nanoparticles.

This study proposes a non-enzymatic glucose sensor fabricated by synthesizing high-purity TiO(2) nanoparticles in thermal plasma and depositing it directly on a substrate and then depositing chitosan-polypyrrole (CS-PPy) conductive polymer films by electrochemical method. The structural properties of the deposited TiO(2) nanoparticles were analyzed by X-ray diffraction (XRD) and dynamic light scattering (DLS) system. The chemical composition and structural properties of the TiO(2) nanoparticle layer and the conductive polymer films were confirmed by X-ray photoelectron spectroscopy (XPS) spectra and scanning electron microscope (SEM). The glucose detection characteristics of the fabricated biosensor were determined by cyclic voltammetry (CV). CS-PPy/TiO(2) biosensor showed high sensitivity of 302.0 µA mM(-1) cm(-2) (R(2) = 0.9957) and low detection limit of 6.7 μM. The easily manufactured CS-PPy/TiO(2) biosensor showed excellent selectivity and reactivity.