meta-C-H arylation and methylation of 3-phenylpropanoic acid and phenolic derivatives were developed using an easily removable nitrile template. The combination of a weakly coordinating U-shaped template and mono-protected amino acid ligand was crucial for the cross-coupling of C-H bonds with organoborons.
Cross-coupling of remote meta-C-H bonds directed by a U-shaped template.
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作者：Wan Li, Dastbaravardeh Navid, Li Gang, Yu Jin-Quan
| 期刊： | Journal of the American Chemical Society | 影响因子： | 15.600 |
| 时间： | 2013 | 起止号： | 2013 Dec 4; 135(48):18056-9 |
| doi： | 10.1021/ja410760f | ||
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