ZnO-CeO(2) Hollow Nanospheres for Selective Determination of Dopamine and Uric Acid.

ZnO-CeO(2) hollow nanospheres have been successfully synthesized via the hard templating method, in which CeO(2) is used as the support skeleton to avoid ZnO agglomeration. The synthesized ZnO-CeO(2) hollow nanospheres possess a large electrochemically active area and high electron transfer owing to the high specific surface area and synergistic effect of ZnO and CeO(2). Due to the above advantages, the resulting ZnO-CeO(2) hollow spheres display high sensitivities of 1122.86 μA mM(-1) cm(-2) and 908.53 μA mM(-1) cm(-2) under a neutral environment for the selective detection of dopamine and uric acid. The constructed electrochemical sensor shows excellent selectivity, stability and recovery for the selective analysis of dopamine and uric acid in actual samples. This study provides a valuable strategy for the synthesis of ZnO-CeO(2) hollow nanospheres via the hard templating method as electrocatalysts for the selective detection of dopamine and uric acid.