Five Ib-type cyclopeptide alkaloids, jubanines F-J (1-5), and three known compounds, nummularine B (6), daechuine-S3 (7), and mucronine K (8) were isolated from the roots of Ziziphus jujuba. Their structures were fully characterized by spectroscopic analyses in combination with chemical derivatization. Compounds 1-3, and 6 were evaluated for their antiviral activity against the porcine epidemic diarrhea virus (PEDV). Compounds 2, 3, and 6 showed potent inhibitory effects on PEDV replication.
Jubanines F-J, cyclopeptide alkaloids from the roots of Ziziphus jujuba.
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作者：Kang Kyo Bin, Ming Gao, Kim Geum Jin, Ha Thi-Kim-Quy, Choi Hyukjae, Oh Won Keun, Sung Sang Hyun
| 期刊： | Phytochemistry | 影响因子： | 3.400 |
| 时间： | 2015 | 起止号： | 2015 Nov;119:90-5 |
| doi： | 10.1016/j.phytochem.2015.09.001 | ||
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