Transgenic tobacco plants stably expressing recombinant FaeG, which is the major subunit and adhesin of K88ad fimbriae, were obtained. Analysis of sera from immunized mice indicates that in mice, the immunogenicity induced by plant-derived FaeG protein is comparable to that generated with traditional approaches.
Production of FaeG, the major subunit of K88 fimbriae, in transgenic tobacco plants and its immunogenicity in mice.
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作者:Huang Yahong, Liang Wanqi, Pan Aihu, Zhou Zhiai, Huang Cheng, Chen Jianxiu, Zhang Dabing
| 期刊: | Infection and Immunity | 影响因子: | 2.800 |
| 时间: | 2003 | 起止号: | 2003 Sep;71(9):5436-9 |
| doi: | 10.1128/IAI.71.9.5436-5439.2003 | ||
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