Here, we describe the molecular and immunological characterization of the bdr gene family of Borrelia turicatae, a relapsing-fever spirochete. Nine bdr alleles belonging to two different subfamilies were sequenced and localized to linear plasmids. Anti-Bdr antiserum was generated and used to analyze Bdr expression in pre- and postinfection isogenic populations. The analyses presented here provide a detailed characterization of the Bdr proteins in a relapsing-fever spirochete species, enhancing our understanding of these proteins at the genus-wide level.
Molecular and immunological analyses of the Borrelia turicatae Bdr protein family.
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作者:Carlyon J A, Roberts D M, Theisen M, Sadler C, Marconi R T
| 期刊: | Infection and Immunity | 影响因子: | 2.800 |
| 时间: | 2000 | 起止号: | 2000 Apr;68(4):2369-73 |
| doi: | 10.1128/IAI.68.4.2369-2373.2000 | ||
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