The title compound, C(36)H(37)ClN(4)O(7)·CH(3)OH, which crystallizes as a methanol solvate, may possess biological activity, which is inherent for a natural peptide or protein. In the crystal, mol-ecules of the title compound form hydrogen-bonded tetra-mers with the solvate mol-ecules acting as bridges as a result of the O-Hâ¯O and N-Hâ¯O inter-molecular hydrogen bonds. Hirshfeld surface analysis was used to study the different types of inter-molecular inter-actions whose contributions are: Hâ¯H = 53.8%, Oâ¯H/Hâ¯O = 19.0%, Câ¯H/Hâ¯C = 14.8%, Clâ¯H/Hâ¯Cl = 5.3%, Nâ¯H/Hâ¯N = 3.2%.
N-tert-Butyl-2-{2-[2-(4-chloro-phen-yl)-4-hy-droxy-1-(5-methyl-isoxazol-3-yl)-5-oxo-2,5-di-hydro-1H-pyrrol-3-yl]-N-(4-meth-oxy-phen-yl)acetamido}-2-(4-meth-oxy-phen-yl)acetamide methanol monosolvate: single-crystal X-ray diffraction study and Hirshfeld surface analysis.
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作者:Shyshkina Mariia O, Sakhno Yana I, Radchenko Oleksandr V, Shishkina Svitlana V, Desenko Sergey M, Chebanov Valentyn A
| 期刊: | Acta Crystallographica Section E: Crystallographic Communications | 影响因子: | 0.500 |
| 时间: | 2021 | 起止号: | 2021 Nov 2; 77(Pt 12):1208-1212 |
| doi: | 10.1107/S2056989021011312 | ||
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