Effect of silver vanadate on the antibiofilm, adhesion and biocompatibility properties of denture adhesive.

Aim: To evaluate the biological and mechanical properties of an adhesive with nanostructured silver vanadate (AgVO(3)). Materials & methods: Specimens in poly(methyl methacrylate) (PMMA) were treated with Ultra Corega Cream (UCCA) denture adhesive with or without AgVO(3). Biofilms of Candida albicans, Candida glabrata and Streptococcus mutans were grown and the viable cells counted. Fluorescence microscopy was used. The viability of the VERO cell and adhesive strength were evaluated. Results: All concentrations of AgVO(3) reduced the biofilm formation and showed no cytotoxic effect. At 5 min and 24 h, UCCA with 5 and 10% AgVO(3) showed better performance, respectively. Conclusion: AgVO(3) promoted the antibiofilm activity of the adhesive, with a positive effect on the adhesive strength, and was biocompatible.