In this work, we developed a targeted glycoproteomic method to monitor the site-specific glycoprofiles and quantities of the most abundant HDL-associated proteins using Orbitrap LC-MS for (glyco)peptide target discovery and QqQ LC-MS for quantitative analysis. We conducted a pilot study using the workflow to determine whether HDL protein glycoprofiles are altered in healthy human participants in response to dietary glycan supplementation.
Quantitative glycoproteomics of high-density lipoproteins.
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作者：Tang Xinyu, Wong Maurice, Tena Jennyfer, Zhu Chenghao, Rhodes Christopher, Zhou Qingwen, Vinjamuri Anita, Oloumi Armin, Boddu Sucharita, Luxardi Guillaume, Maverakis Emanual, Lebrilla Carlito B, Zivkovic Angela M
| 期刊： | RSC Advances | 影响因子： | 4.600 |
| 时间： | 2022 | 起止号： | 2022 Jun 23; 12(29):18450-18456 |
| doi： | 10.1039/d2ra02294j | ||
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