The SYBR Green I malaria drug sensitivity assay: performance in low parasitemia samples

SYBR Green I 疟疾药物敏感性试验:在低寄生虫血症样本中的表现

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作者:Matthias G Vossen, Sandra Pferschy, Peter Chiba, Harald Noedl

Abstract

Validation of the sensitivity of the SYBR Green I in vitro test against an enzyme-linked immunosorbent assay (ELISA)-based drug sensitivity assay. Our results suggest that the SYBR Green I assay is a fast and inexpensive malaria drug screening assay for laboratory use. However, because of its lack of sensitivity in whole blood samples its usefulness for testing clinical samples may be limited.

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