Abstract
INTRODUCTION: Cardiovascular disease (CVD) accounts for 18 million deaths per year, disproportionately burdens under-represented racial and ethnic groups, and has economic costs greater than any other health condition. Participation in youth sport may be an effective strategy to improve CVD-related risk factors but studies of youth sport participation have shown mixed results for improving health outcomes. Therefore, the objective of this systematic review is to examine how participation in youth sport contributes to physical activity levels and CVD risk factors in children aged 5-14 years old. A secondary objective is to determine if outcomes are different in racial and ethnic groups. METHODS AND ANALYSIS: The search will encompass studies published in English, Spanish or Portuguese between January 1995 and April 2024, including five databases (PubMed, Medline, Embase, Cochrane Library and SPORTDiscus). Studies will be included if they are experimental or observational studies, conducted in youths of any health background and assess the relationship of sport participation to physical activity levels or CVD risk factors. Studies must report on at least one of the following outcomes: (1) physical activity levels, (2) blood pressure, (3) lipid fractions, (4) body mass index (5) central adiposity, (6) systemic inflammation and (7) glucose levels/insulin resistance. Study quality will be assessed using the Cochrane Risk of Bias version 1 tool. Narrative descriptions and summary tables will be created to describe studies, results and methodological quality and be synthesised by subsets of studies based on study design and outcomes. In the systematic review, we will categorise the included studies into two subgroups (ie, observational studies, experimental studies) and meta-analyse them separately prior to exploring sources of heterogeneity. ETHICS AND DISSEMINATION: Ethical approval is not required. The results will be disseminated via peer-reviewed publication and presentation at conferences relevant to this field. PROSPERO REGISTRATION NUMBER: CRD42023427219.