Abstract
WHAT IS ALREADY KNOWN ABOUT THIS TOPIC? Previous studies have illustrated the benefits of physical activity on cardiometabolic multimorbidity (CMM), while limited studies have concentrated on the trajectory of CMM progression. WHAT IS ADDED BY THIS REPORT? Through multi-stage regression analysis, we found that physical activity could reduce the risk of CMM incidence. Participants initially free of cardiometabolic diseases (CMDs) may benefit more from engaging in recommended physical activity. WHAT ARE THE IMPLICATIONS FOR PUBLIC HEALTH PRACTICE? Adults, especially those initially free of CMDs, should engage in WHO-recommended physical activity as early as possible to prevent CMD incidence and further progression.