Evaluation of Rapid Diagnostic Tests for Assessment of Hepatitis B in Resource-Limited Settings

在资源匮乏地区评估快速诊断测试对乙型肝炎的诊断价值

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Abstract

Chronic Hepatitis B (HBV) is the most important cause of liver disease worldwide. There is a need for low-cost tests to aid in diagnosis and management of HBV infection in resource-limited settings. We evaluated the utility of several rapid diagnostic tests (RDT) in three different continents (Europe, South America, Africa). The HBsAg RDT showed optimal sensitivity and specificity. The anti-HBeAb RDT showed acceptable sensitivity and excellent specificity. Our results suggest that these RDTs could be used for screening and management of HBV.

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