atSNPInfrastructure, a case study for searching billions of records while providing significant cost savings over cloud providers

atSNPInfrastructure 是一个案例研究,展示了如何在搜索数十亿条记录的同时,相比云服务提供商显著降低成本。

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Abstract

We explore the feasibility of a database storage engine housing up to 307 billion genetic Single Nucleotide Polymorphisms (SNP) for online access. We evaluate database storage engines and implement a solution utilizing factors such as dataset size, information gain, cost and hardware constraints. Our solution provides a full feature functional model for scalable storage and query-ability for researchers exploring the SNP's in the human genome. We address the scalability problem by building physical infrastructure and comparing final costs to a major cloud provider.

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