N4-phenyl modifications of N2-(2-hydroxyl)ethyl-6-(pyrrolidin-1-yl)-1,3,5-triazine-2,4-diamines enhance glucocerebrosidase inhibition by small molecules with potential as chemical chaperones for Gaucher disease

N2-(2-羟基)乙基-6-(吡咯烷-1-基)-1,3,5-三嗪-2,4-二胺的N4-苯基修饰可增强小分子对葡萄糖脑苷脂酶的抑制作用，这些小分子具有作为戈谢病化学伴侣的潜力。