Generation of the human pluripotent stem cell lines KUMi005-A from a patients with multiple myeloma
从多发性骨髓瘤患者体内生成人类多能干细胞系 KUMi005-A
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作者:Ji-Hea Kim, Ji-Hyeon Hong, Ka-Won Kang, Byung-Hyun Lee, Young Park, Byung-Soo Kim
| 期刊: | Stem Cell Research | 影响因子: | 0.800 |
| 时间: | 2022 | 起止号: | 2022 Dec:65:102939. |
| doi: | 10.1016/j.scr.2022.102939 | 种属: | Human |
| 研究方向: | 发育与干细胞、肿瘤 | 疾病类型: | 骨髓瘤 |
| 细胞类型: | 干细胞 | |
Abstract
Multiple myeloma (MM) progresses with abnormal monoclonal proliferation and accumulation of malignant plasma cells in the bone marrow. We established human induced pluripotent stem cells (iPSCs), KUMi005-A, from bone marrow samples of a patient with MM. This reprogrammed cell line has similar characteristics to human embryonic stem cells, such as proliferation properties and pluripotency. KUMi005-A iPSCs may be applicable in MM disease modeling and cell-based therapies.
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