Abstract
BACKGROUND: Valid skinfold thickness (SFT) equations for the prediction of body fat are currently unavailable for South Asian women and would be a potentially robust field tool. Our aim was to assess the validity of existing SFT equations against deuterium ((2)H(2)O) dilution and, if invalid, to develop and validate an SFT equation for % fat mass (%FM) in Sri Lankan women. METHODS: H(2)O dilution was used with Fourier transform infrared (FTIR) spectroscopy as the criterion method for the assessment of %FM in urban Sri Lankan women (30-45 years). This data was used to assess the validity of available SFT equations and to generate and validate a new SFT equation for the prediction of %FM against the criterion method. Women (n = 164) were divided into validation and cross-validation groups for the development and validation of the new equation. The level of agreement between the %FM calculated by the final derived prediction equation and the %FM obtained by (2)H(2)O dilution was assessed using Pearson's correlation coefficient (R) and Bland Altman plots. Student's t test was used to assess over- or underestimation, and significance was set at p < 0.05. RESULTS: Existing equations significantly (p < 0.001) underestimated %FM compared with the (2)H(2)O dilution method. The final equation obtained was %FM = 19.621 + (0.237*weight) + (0.259*triceps). When compared with (2)H(2)O dilution, %FM by the equation was not significantly different. There was a significant (p < 0.001) correlation between %FM by the reference method and %FM by the equation. The limit of agreement by Bland Altman plot was narrow with a small mean positive bias. CONCLUSIONS: Existing SFT equations were not applicable to this population. The new equation derived was valid. We report a new SFT equation to predict %FM in women of South Asian ancestry suitable for field use.