Steven's Johnson syndrome with toxic epidermal necrolysis due to thalidomide in a case of multiple myeloma

因沙利度胺治疗多发性骨髓瘤并发史蒂文斯-约翰逊综合征伴中毒性表皮坏死松解症

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Abstract

Thalidomide developed in 1954 for morning sickness had proven to be a teratogen and hence was withdrawn from market. Resurgence of thalidomide began as an immunomodulator when it was shown to be effective in the management of multiple myeloma and many conditions like erythema nodosum leprosum, graft versus host disease, recurrent aphthous ulcers etc. We report a case of Stevens Johnson syndrome-toxic epidermal necrolysis developing in an elderly male who was prescribed thalidomide after being diagnosed with multiple myeloma.

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