Prognostic Factors of Clinical and Economic Outcomes of Hip Arthroplasty in a Developing Country: A Multilevel Analysis with a 4-Year Cohort Study

发展中国家髋关节置换术临床和经济结果的预后因素:一项为期4年的队列研究的多层次分析

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Abstract

INTRODUCTION: This study is aimed at estimating the 30-day postoperative mortality rate and total costs of the medical episode, as well as determining prognostic factors associated with these outcomes for adult patients who have undergone total hip arthroplasty (THA) in Colombia's contributory health system. METHODS: This was a retrospective cohort using administrative data and included adult patients enrolled in Colombia's contributory health system who underwent THA between the years 2011 and 2014. Outcomes were 30-day mortality ICU admissions, and the 1-year rate of fractures and revisions as well as the total cost of the medical episode incurred by the third-payer for 90 days following the procedure. Multilevel linear regression models were also generated to determine the prognostic factors associated with the outcomes presented. RESULTS: The study included 17,289 patients, with an average age of 67 years. Outcome rates were calculated per 100 surgeries, resulting in 2.15 for mortality, 3.41 for ICU admissions, 2.42 for revision hip arthroplasty and 0.62 for periprosthetic fractures. This study found the age and Charlson Comorbidity Index were associated with mortality and complications, and that being female and performing the procedure in the capital city were protective factors. It also found that the median total cost of the medical episode was USD $ USD$2742.161 (p25-p75: 353.092-3291.747). The multivariate model found increasing trends in cost as age and CCI scores rose, and higher costs in the Atlantic region. CONCLUSIONS: Colombia has higher rates of complications from THA than other countries but lower health system costs. For these patients, age, CCI and the geographic region are factors that are associated with mortality, complications, and health system costs.

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