Cytotoxic T cell adoptive immunotherapy as a treatment for nasopharyngeal carcinoma

细胞毒性T细胞过继免疫疗法治疗鼻咽癌

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Abstract

Epstein-Barr virus (EBV) is associated with nasopharyngeal carcinoma (NPC). We assess the safety and tolerability of adoptive transfer of autologous cytotoxic T lymphocytes (CTLs) specific for the EBV latent membrane protein (LMP) in a patient with recurrent NPC. After infusion, the majority of pulmonary lesions were no longer evident, although the primary tumor did not regress.

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