ATM Regulation of the Cohesin Complex Is Required for Repression of DNA Replication and Transcription in the Vicinity of DNA Double-Strand Breaks

ATM对黏连蛋白复合物的调控是抑制DNA双链断裂附近DNA复制和转录所必需的

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作者:Thomas E Bass ,Donald E Fleenor ,Paige E Burrell ,Michael B Kastan

Abstract

Multiple members of the cohesin complex are involved in the regulation of DNA replication and transcription in the vicinity of DNA double-strand breaks and their role(s) are regulated by the ATM kinase.

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