Serum sickness following rabbit anti-thymocyte globulin for acute vascular renal allograft rejection

急性血管肾移植排斥反应后使用兔抗胸腺细胞球蛋白引起的血清病

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Abstract

A simultaneous pancreas-kidney transplant recipient developed serum sickness manifesting with severe upper limb allodynia, arthralgia and myalgia 17 days following rabbit anti-thymocyte globulin (rATG) infusion for biopsy-proven vascular rejection. Rapid resolution of symptoms followed treatment with high-dose glucocorticoids. rATG is increasingly favoured over equine ATG in solid-organ transplantation, and although rATG has a superior safety profile, it is important to maintain a high index of suspicion for serum sickness.

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