Malignant hypertension with thrombotic microangiopathy and persistent acute kidney injury (AKI)

恶性高血压伴血栓性微血管病和持续性急性肾损伤(AKI)

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Abstract

Two cases of malignant hypertension presenting with acute kidney injury, thrombocytopenia and hemolytic anemia are presented. In both patients a prolonged duration of renal replacement therapy was required. The plasma levels of ADAMTS13 enzyme were not helpful in delineating the precise pathogenesis in both cases, as the decrements were not severe. We discuss the clinic-pathologic correlation of the biopsy findings and persistence of AKI.

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