Annual audit of three year outcome in very low birthweight infants

Annual odds ratios, standardised for known confounding variables, were used to examine trends in outcome at 3 years of age among 1499 infants of less than 1500 g birth weight admitted to a regional referral centre between 1980 and 1989. Despite improved survival, the chance of survival with a major disability or with cerebral palsy was unchanged. The likelihood of dying or surviving with a major disability significantly reduced during the decade.