Two Cases Report of Intrathecal Tigecycline Therapy for Intracranial Infection with Acinetobacter baumannii and Review of Literatures

两例鞘内注射替加环素治疗鲍曼不动杆菌颅内感染的病例报告及文献复习

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Abstract

OBJECTIVE: To explore the treatment scheme for intracranial infection with Acinetobacter baumannii. METHODS: We retrospective analyzed two cases of patients of intracranial infection with Acinetobacter baumannii. RESULTS: The intracranial infection was controlled effectively by the scheme to intravenous"tigecycline + cefperazone-sulbactam"combined with intrathecal tigecycline injection, the two patients recover well with 21 months' follow-up. CONCLUSIONS: Tigecycline-based drug scheme combined with intrathecal tigecycline injection can achieve the effect of controlling intracranial infection. Lumbar cisterna drainage tube plays a major role in controlling intracranial infection.

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