[Retracted] 3‑β‑Εrythrodiol isolated from Conyza canadensis inhibits MKN‑45 human gastric cancer cell proliferation by inducing apoptosis, cell cycle arrest, DNA fragmentation, ROS generation and reduces tumor weight and volume in mouse xenograft model

[已撤稿] 从加拿大飞蓬(Conyza canadensis)中分离得到的3-β-赤藓二醇通过诱导细胞凋亡、细胞周期阻滞、DNA片段化和活性氧(ROS)生成来抑制MKN-45人胃癌细胞增殖,并在小鼠异种移植模型中降低肿瘤重量和体积。

阅读:1

Abstract

Following the publication of the above paper, an interested reader drew to our attention that a number of apparent anomalies existed with the data presented in the above paper; specifically, there appeared to be strikingly similar and replicated patternings of the cells within the cellular images featured in Figs. 4A‑D and 5A‑D (affecting all the figure parts). Secondly, Fig. 4 in the above study appeared to have been a reproduction of Fig. 3 from following paper featuring different authors, albeit Fig. 4 appeared in greyscale, and not in colour, in the above paper [Wan G, Tao J‑G, Wang G‑D, Liu. S‑P, Zhao H‑X and Liang Q‑D: In vitro antitumor activity of the ethyl acetate extract of Potentilla chinensis in osteosarcoma cancer cells. Mol Med Rep 14: 3634‑3640, 2016]. Following an internal enquiry, the Editor of Oncology Reports was able to verify the claims made by the interested reader; therefore, in view of the number of potential anomalies that have been identified and owing to a lack of overall confidence in the presented data, the Editorial Board have decided to retract the above paper from the publication. The Journal were also contacted independently by the authors, who wished to retract the paper on account of not being able to reproduce the results shown in Fig.. 2. The Editor apologizes to the readership of the Journal for any inconvenience caused. [the original article was published in Oncology Reports 35: 2328‑2338, 2016; DOI: 10.3892/or.2016.4610].

特别声明

1、本页面内容包含部分的内容是基于公开信息的合理引用;引用内容仅为补充信息,不代表本站立场。

2、若认为本页面引用内容涉及侵权,请及时与本站联系,我们将第一时间处理。

3、其他媒体/个人如需使用本页面原创内容,需注明“来源:[生知库]”并获得授权;使用引用内容的,需自行联系原作者获得许可。

4、投稿及合作请联系:info@biocloudy.com。