Wild-Type TP53 Predicts Poor Prognosis in Patients with Gastric Cancer
野生型 TP53 预测胃癌患者预后不良
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作者:Wenhong Deng, Qiongyu Hao, Jaydutt Vadgama, Yong Wu
| 期刊: | J Cancer Sci Clin Ther | 影响因子: | |
| 时间: | 2021 | 起止号: | 2021 Mar 18;5(1):134-153. |
| doi: | 10.26502/jcsct.50790107 | 种属: | Human |
| 方法学: | FCM、IF、IHC-P、WB | 研究方向: | 肿瘤 |
| 疾病类型: | 胃癌 | |
Conclusion
our results indicate that the status of TP53 mutation in GC is significantly correlated with clinical or molecular categories and that the prognosis of GC patients with WT TP53 is worse than that of patients with mutant TP53. Therefore, our data emphasize the importance of distinguishing TP53 WT to predict poor overall survival and relapse-free survival in patients with GC.
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