Copper-Catalyzed Difluoroalkylation Reaction

铜催化二氟烷基化反应

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Abstract

This review describes recent advances in copper-catalyzed difluoroalkylation reactions. The RCF(2) radical is generally proposed in the mechanism of these reactions. At present, various types of copper-catalyzed difluoroalkylation reactions have been realized. According to their characteristics, we classify these difluoroalkylation reactions into three types.

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