Abstract
Far-UV irradiation of Bacteroides fragilis cells under anaerobic conditions resulted in the induction of a new 95,000-molecular-weight protein and the increased synthesis of two proteins with molecular weights of 90,000 and 70,000. The latter two proteins were synthesized in small amounts in unirradiated cells. The induction of a 37,000- to 40,000-molecular-weight protein was not observed in irradiated B. fragilis cells. Caffeine, which affected the survival of irradiated B. fragilis cells and reduced host cell-mediated UV reactivation, specifically inhibited the induction of the 95,000-, 90,000-, and 70,000-molecular-weight proteins. Sodium arsenite did not affect the induction of the three inducible proteins or the survival of irradiated B. fragilis cells.