Association of interferon-gamma and interleukin 10 genotypes and serum levels with partial clinical remission in type 1 diabetes

干扰素-γ和白细胞介素10基因型及血清水平与1型糖尿病部分临床缓解的相关性

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作者：Alizadeh,B Z,Hanifi-Moghaddam,P,Eerligh,P,van der Slik,A R,Kolb,H,Kharagjitsingh,A V,Pereira Arias,A M,Ronkainen,M,Knip,M,Bonfanti,R,Bonifacio,E,Devendra,D,Wilkin,T,Giphart,M J,Koeleman,B P C,Nolsøe,R,Mandrup Poulsen,T,Schloot,N C,Roep,B O
期刊：Clinical and Experimental Immunology影响因子：3.800
时间：2006起止号：2006 Sep;145(3):480-4
doi：10.1111/j.1365-2249.2006.03172.x研究方向： 细胞生物学、代谢
疾病类型： 糖尿病

Abstract

We studied whether serum interferon (IFN)-gamma or interleukin (IL)-10 levels and their corresponding functional polymorphic genotypes are associated with partial remission of type 1 diabetes (T1D). A multi-centre study was undertaken in patients with newly diagnosed T1D and matched controls. T1D patients were followed for 3 months and characterized for remission status. Partial clinical remission was defined as a daily insulin dose

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