A novel, accurate, and non-invasive liquid biopsy test to measure cellular immune responses as a tool to diagnose early-stage lung cancer: a clinical trials study

一种新颖、准确且非侵入性的液体活检测试,用于测量细胞免疫反应作为诊断早期肺癌的工具:一项临床试验研究

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作者:Shafrira Shai, Fernando Patolsky, Hagai Drori, Eyal J Scheinman, Eyal Davidovits, Giora Davidovits, Shoval Tirman, Nadir Arber, Amit Katz, Yochai Adir

Conclusion

The improved protocol of the novel cellular immune metabolic response based test detects stage I and stage II of lung cancer with high specificity and sensitivity, with low material costs and fast results.

Results

In the later clinical trial, an improved test protocol was applied and resulted in increased test accuracy. Specificity of the test increased to 94.0% and test sensitivity increased to 97.3% in lung cancer stage I, by using the improved protocol.

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