Subtumoral analysis of PRINT nanoparticle distribution reveals targeting variation based on cellular and particle properties

PRINT 纳米粒子分布的肿瘤下分析揭示了基于细胞和粒子特性的靶向变化

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作者:Luke E Roode, Hailey Brighton, Tao Bo, Jillian L Perry, Matthew C Parrott, Farrell Kersey, J Chris Luft, James E Bear, Joseph M DeSimone, Ian J Davis

From the clinical editor

Particle Replication in Non-Wetting Templates (PRINT) technology allows the production of nanoparticles with uniform size. The authors in the study utilized PRINT-produced nanoparticles to investigate specific tumor uptake by multi-color flow cytometry and in vivo confocal tumor imaging. This approach allowed further in-depth correlation between nanoparticle properties and tumor cells and should improve future design.

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