Utility of immunohistochemical staining for the diagnosis of Extra-adrenal mediastinal paraganglioma

免疫组织化学染色在肾上腺外纵隔副神经节瘤诊断中的应用

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Abstract

Extra-adrenal, mediastinal paraganglioma are rare tumors that origin from sympathetic ganglia. Common diagnostic steps include CT, MRI and PET-Scan. We present a case where immunohistochemical staining was an essential step for final diagnosis in a patient without symptoms of endocrine activity and an uncommon location of this tumor entity. In combination with clinical particularities on the origin of the tumor and characteristic morphology, the immunohistochemical staining of tumor tissue is a necessary diagnostic tool for paraganglioma.

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