Abstract
Apocynum pictum (A. pictum) honey is rich in effective ingredients including flavonoids, terpenes, and alkaloids that are beneficial to human health. In this study, widely targeted metabolomics were used to detect the plant-derived secondary metabolites of the same batch of A. pictum honey from 2022 to 2024, in order to explore whether storage time changes the quality of A. pictum honey, especially the content of plant-derived secondary metabolites with important health benefits. The results showed that storage time had no significant effect on the content of sugars, proteins, and other major components in A. pictum honey. At the same time, we also found that although storage time had an impact on the content of some secondary metabolites such as flavonoids in A. pictum honey, the changes in the content of the characteristic active ingredient, hyperoside, in A. pictum honey were not significant. These findings suggest that storage time has a minimal impact on the quality of A. pictum honey. This study provides a theoretical basis for the rational storage of A. pictum honey.