The prognostic value of Niemann-Pick C1-like protein 1 and Niemann-Pick disease type C2 in hepatocellular carcinoma
尼曼匹克C1样蛋白1及尼曼匹克病C2型对肝细胞癌的预后价值
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作者:Ke-Ji Chen, Ri-Ming Jin, Chun-Chao Shi, Rui-Liang Ge, Lei Hu, Qi-Fei Zou, Quan-Yu Cai, Guang-Zhi Jin, Kui Wang
| 期刊: | Journal of Cancer | 影响因子: | 3.300 |
| 时间: | 2018 | 起止号: | 2018 Jan 1;9(3):556-563. |
| doi: | 10.7150/jca.19996 | 研究方向: | 肿瘤 |
| 疾病类型: | 肝癌 | 细胞类型: | 其它细胞 |
Conclusion
NPC1L1 and NPC2 were lowly expressed in HCC compared with peritumoral liver tissues, and low expression of NPC1L1 and NPC2 in HCC tissues may indicate poor outcome of HCC patients after surgery. NPC1L1/NPC2 combination is an independent prognostic factor for OS and TTR in postoperative HCC patients.
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