Who Is the Intermediate Host of RNA Viruses? A Study Focusing on SARS-CoV-2 and Poliovirus

谁是RNA病毒的中间宿主?一项针对SARS-CoV-2和脊髓灰质炎病毒的研究

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作者:Carlo Brogna ,Domenico Rocco Bisaccia ,Vincenzo Costanzo ,Gennaro Lettieri ,Luigi Montano ,Valentina Viduto ,Mark Fabrowski ,Simone Cristoni ,Marina Prisco ,Marina Piscopo

Abstract

The COVID-19 pandemic has sparked a surge in research on microbiology and virology, shedding light on overlooked aspects such as the infection of bacteria by RNA virions in the animal microbiome. Studies reveal a decrease in beneficial gut bacteria during COVID-19, indicating a significant interaction between SARS-CoV-2 and the human microbiome. However, determining the origins of the virus remains complex, with observed phenomena such as species jumps adding layers to the narrative. Prokaryotic cells play a crucial role in the disease's pathogenesis and transmission. Analyzing previous studies highlights intricate interactions from clinical manifestations to the use of the nitrogen isotope test. Drawing parallels with the history of the Poliovirus underscores the need to prioritize investigations into prokaryotic cells hosting RNA viruses. Keywords: SARS-CoV-2; Sabin; bacteriophage; gut microbiome; poliovirus; toxins; vaccine.

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