Disruption of 3D MCF-12A breast cell cultures by estrogens--an in vitro model for ER-mediated changes indicative of hormonal carcinogenesis

雌激素破坏 3D MCF-12A 乳腺细胞培养物——ER 介导变化的体外模型,提示激素致癌作用

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作者:Stephanie Marchese, Elisabete Silva

Conclusion

This new model offers the opportunity to better understand the role of the ER and GPER in the morphogenesis of breast glandular structure as well as the events implicated in breast cancer initiation and progression.

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