Actin filament length tunes elasticity of flexibly cross-linked actin networks

肌动蛋白丝长度调节柔性交联肌动蛋白网络的弹性

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Abstract

Networks of the cytoskeletal biopolymer actin cross-linked by the compliant protein filamin form soft gels that stiffen dramatically under shear stress. We demonstrate that the elasticity of these networks shows a strong dependence on the mean length of the actin polymers, unlike networks with small, rigid cross-links. This behavior is in agreement with a model of rigid filaments connected by multiple flexible linkers.

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