Abstract
Indeterminate pulmonary nodules are commonly encountered and often result in costly and invasive procedures that eventually turn out to be unnecessary. Current prediction models can help to estimate the pretest probability of cancer and assist in determining a strategy of observation with serial imaging for a low pretest probability of cancer, and a more aggressive approach for those patients with a high pretest probability. However, the majority of patients will have an intermediate pretest probability which becomes complex. Decisions for further management are often based on preference by the clinician with the majority of physicians not following current guidelines in the management of pulmonary nodules. Poor adherence to pulmonary nodule guidelines is multifactorial with a variety of factors coming into play. These include inappropriate advice given by the radiologist, patient age, comorbidities, patient preference, and physician's technical skill all influencing the decision making.