Active and passive immunization in the adult rabbit ileal loop model as an assay for production of antitoxin immunity by cholera vaccines

以成年兔回肠袢模型进行主动和被动免疫,作为霍乱疫苗产生抗毒素免疫力的检测方法

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Abstract

Three field trial cholera vaccines did not induce antitoxic immunity. A choleragenic toxin induced high-serum neutralizing antibody, but protection to loop challenge with toxin was minimal.

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