Abstract
Foot-and-mouth disease is an acute, highly infectious, and economically significant transboundary animal disease. Vaccination is an efficient and cost-effective measure to prevent the transmission of this disease. The primary way that foot-and-mouth disease spreads is through direct contact with infected animals, although it can also spread through contact with contaminated environments. This paper uses a diffuse foot-and-mouth disease model to account for the efficacy of vaccination in managing the disease. First, we transform an age-space structured foot-and-mouth disease into a diffusive epidemic model with nonlocal infection coupling the latent period and the latent diffusive rate. The basic reproduction number, which determines the outbreak of the disease, is then explicitly formulated. Finally, numerical simulations demonstrate that increasing vaccine efficacy has a remarkable effect than increasing vaccine coverage.