C1q/TNF-Related Proteins 1, 6 and 8 Are Involved in Corneal Epithelial Wound Closure by Targeting Relaxin Receptor RXFP1 In Vitro
C1q/TNF 相关蛋白 1、6 和 8 通过体外靶向松弛素受体 RXFP1 参与角膜上皮伤口闭合
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作者:Hagen Fabian Nicolaus, Thomas Klonisch, Friedrich Paulsen, Fabian Garreis
Conclusions
Our findings demonstrate a novel role for CTRP1, CTRP6, and CTRP8 in corneal epithelial wound closure and suggest an involvement of the relaxin receptor RXFP1 signaling pathway. This could be a first step toward new approaches for pharmacological and therapeutic intervention.
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