First isolation of two colistin-resistant emerging pathogens, Brevundimonas diminuta and Ochrobactrum anthropi, in a woman with cystic fibrosis: a case report

首次从一名囊性纤维化女性患者体内分离出两种耐粘菌素的新兴病原体:微小短波单胞菌和人赭色杆菌:病例报告

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Abstract

INTRODUCTION: Cystic fibrosis afflicted lungs support the growth of many bacteria rarely implicated in other cases of human infections. CASE PRESENTATION: We report the isolation and identification, by 16S rRNA amplification and sequencing, of two emerging pathogens resistant to colistin, Brevundimonas diminuta and Ochrobactrum anthropi, in a 17-year-old woman with cystic fibrosis and pneumonia. The patient eventually responded well to a 2-week regime of imipenem and tobramycin. CONCLUSION: Our results clearly re-emphasize the emergence of new colistin-resistant pathogens in patients with cystic fibrosis.

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