An Unsettled Debate About the Potential Role of Infection in Pathogenesis of Atherosclerosis

关于感染在动脉粥样硬化发病机制中的潜在作用,目前仍存在争议

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Abstract

Association of infection with atherosclerosis is by no means new. Several sero-epidemiological and pathologic studies as well as animal models have shown a link between infection and atherosclerosis. Exciting discoveries in recent times related to role of inter-individual genetic variation in modulating inflammatory response to infection have reignited the enthusiasm in proving a causal link between infection and atherosclerosis. The purpose of this article was to review and analyze the available evidence linking infection with atherosclerosis.

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