Abstract
We present a case of a 79-year-old male with a Salmonella enteritidis prosthetic knee joint infection preceded by an episode of profuse diarrhea. The infection was treated with ceftriaxone antibacterial chemotherapy, and an arthroscopic knee joint washout. The initial treatment failed to eradicate the Salmonella infection. A second open washout procedure with the replacement of knee joint insert was performed along with the addition of ciprofloxacin to the ongoing ceftriaxone which eventually eradicated the infection. Although S. enteritidis is a very rare cause of prosthetic knee infection, suspicion of Salmonella as a potential causative agent should be borne in mind particularly if the onset of the symptoms is preceded by gastrointestinal manifestations.