The Rényi divergence enables accurate and precise cluster analysis for localization microscopy

Rényi 散度可实现定位显微镜的准确和精确的聚类分析

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作者:Adela D Staszowska, Patrick Fox-Roberts, Liisa M Hirvonen, Christopher J Peddie, Lucy M Collinson, Gareth E Jones, Susan Cox

Results

Here, we describe how the Rényi divergence can be used for cluster radius measurements in localization microscopy data. We demonstrate that the Rényi divergence can operate with high levels of background and provides results which are more accurate than Ripley's functions, Voronoi tesselation or DBSCAN. Availability and implementation: The data supporting this research and the software described are accessible at the following site: https://dx.doi.org/10.18742/RDM01-316. Correspondence and requests for materials should be addressed to the corresponding author.

Supplementary Information

Supplementary data are available at Bioinformatics online.

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